Construction Industry” (08/04/1992) into their program as possible. A variety of epidemiological studies have investigated the noise-solvent relationship in people. Overall, the evidence strongly suggests that combined exposure to noise and organic solvents can have interactive results , during which solvents exacerbate noise-induced impairments despite the fact that the noise intensity is beneath the permissible restrict value. In addition to the synergistic effects with solvents, noise may have additive, potentiating, or synergistic ototoxicity with asphyxiants and metals . See Appendix D for additional information and additional sources of data on this matter.