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biomaterial. However, this role assumes the ability of the biomaterial to activate DCs by direct contact between the material and the cells . It is usually recommended that biomaterials prime dendritic cells by way of PRR signaling pathways and depending on which PRR receptor is triggered, maturation or inhibition of DCs can be induced, contributing respectively to the lengthening of the immune response to biomaterials and the delay of wound therapeutic or to the down-regulation of the inflammatory response . Cell adhesion to protein-coated biomaterials

 

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