Alzheimer’s disease, with a weaker association with increased admissions for dementia associated with ozone with a 5-day lag time . A number of earlier studies have shown relationships between ambient air PM2.5 and decreased cognitive function in older populations. Furthermore, mitochondrion may be a site of ROS generation also in response to metallic environmental pollutants, as shown with cadmium or hexavalent chromium that trigger ROS production from the electron
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