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mycosporine-like amino acids.Mycosporine-like amino acids can be transferred through the food web from phytoplankton to zooplankton,200 thus conferring tolerance to UV radiation to the latter organisms. Adequate vitamin D in the phytoplankton food source also enhances UV-tolerance of certain zooplankton. Furthermore, several zooplankton species can sense and escape UV radiation by migrating to deeper waters. This migration transports nutrients and carbon vertically within the water column and changes nutrient availability for phytoplankton as well as the availability of zooplankton as food for fish. The weight of risk vs. benefit for sun exposure depends on the size of the effect and the proportion that can be attributed to lowhigh exposure to UV radiation as well as the total burden of UV-related health outcomes. While there is some confidence in the burden of disease that can be attributed to overexposure to UV radiation,he range of diseases caused by low sun exposure and the size of any potential risks are unclear. Exposure to the sun may have effects that are not mediated by vitamin D106 A recent study showed that irradiation with UV-A reduced blood pressure temporarily, possibly through release of nitric oxide stores in the skin reviewed in ref.107. In a study in southern Sweden, adults reporting a habit of intentional sun exposure had a lower risk of cardiovascular disease and non-cancernon-CVD death than those who avoided sun exposure.108 Compared to the highest sun exposure group, life expectancy in sun-avoiders was reduced by 6–1 years; avoidance of sun exposure was a risk factor for death of similar magnitude to smoking in this study.108Whether this association can be attributed to vitamin D, other UV-induced pathways, or differences in unmeasured lifestyle factors e.g., exercise between people with high and low sun exposure, cannot be determined. For any individual, there is likely to be an optimal level of exposure, but this is highly variable and difficult to define. There are both direct and indirect effects on health. Direct adverse effects include skin cancers, cataracts, and reactivation of some viral infections. The best defined direct benefit is the synthesis of vitamin D. Indirect effects include those resulting from changes in food quality and disinfection of surface waters used for drinking . In another study,6 simulations with a chemistry-climate model forced by three different emissions scenarios RCP5, RCP0, and RCP5 suggest that total ozone columns in the tropics will be lower by the end of the 21st century compared to the 1960s in all scenarios with the largest decrease in the RCP0 scenario. For the RCP0 scenario the concomitant increase in DNA-weighted UV irradiance reaches 15% in specific tropical regions e.g., in South America, southern Asia and over large parts of the Pacific Ocean. Having said all that, there is clearly considerable scientific and public interest in being able to identify a recovery in ozone

the louisville cardinals football full printing flip flops 2
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