Pizarro quickly realized these divisions and took advantage of them. The cause of the civil war was an epidemic of smallpox that spread throughout the kingdom among South Indians after the Spaniards settled in Panama and Colombia, killing the Inca Huayna Emperor and most the king’s court was circa 1526, after that it killed the person appointed to succeed the king, Ninan Cuyuchi. AND SHE LIVED HAPPILY EVER AFTER DOGS POSTER. These deaths led to a competition for the throne between Atahualpa and his brother, Huascar. If there was no epidemic, the Spanish would have faced a unified empire.