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Research from the Bucharest Early Intervention Project (BEIP) is often cited as demonstrating that residential institutions negatively impact the wellbeing of children. The BEIP selected orphanages in Bucharest, Romania that raised abandoned children in socially and emotionally deprived environments in order to study the changes in development of infants and children after they had been placed with specially trained foster families in the local community. This powerful study demonstrated how the lack of loving attention typically provided to children by their parents or caregivers is pivotal for optimal human development, specifically of the brain; adequate nutrition is not enough. Further research of children who were adopted from institutions in Eastern European countries to the US demonstrated that for every 3.5 months that an infant spent in the institution, they lagged behind their peers in growth by 1 month. Further, a meta-analysis of research on the IQs of children in orphanages found lower IQs among the children in many institutions, but this result was not found in the low-income country setting.

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